you are on a PC so please bear with me, I am not overly familiar with your platform.
First, what version of PS were you using before?
Is your default preview space Adobe RGB 1998? If it is, you are probably seeing a far more acute preview - I don't know what spaces are available by name but you may want to change your working color space to your monitors settings. If you are set to default to your monitor's color space, try changing to Adobe RGB 98 or 03. If you do allot of printing to cmyk, you may consider using colormatch as your default space, not my favorite but it is the closest to cmyk from the rgb spectrum. It is the default space for most rgb light imaging systems and doesn't have the oversaturated red of the Adobe 98 space.