I have the same problem with CS. Not only does the image open at a quite small size, but it is all the way to the left of the workspace and thus the left side of the photo is under the toolbar. When I then click on the Hand tool, and choose Fit to screen, it fits it with the left side still under the toolbar. If I move it first, then do a fit to screen the same thing happens. So you can no longer use fit to screen. I have checked all the preferences and there is no setting for screen location or size that I can find. Photoshop 7 opened the image properly and fit to screen worked properly. I have heard a rumor that this problem is caused the by the activation process. I do not recall having the problem for the first few weeks before I activated the program. This is a very serious an irritating problem.