I purchased one a short while back, and it rarely leaves the camera. Need a wide aperture for nice backgrounds? You've got it...bokeh on a par with the 85mm 1.4. Need to slow down the shutter for blurred motion? Stability at full zoom down to a 1/20th of a sec. HANDHELD. It's been a near-religious experience. Remember, you've got a 105 to 300mm equiv. crop going on here...and that long end is incredibly flattering to the female face and form.
Here's a shot of Mayan Lee, 1/125th @ f/3.3, 200mm (300mm equiv.). Straight from camera (Fuji S2), no retouching - just added the copyright, rotated and resized.
(shot through leaves to achieve the effect)