I first created a layer above the image, sampled a color close to the hotspot. With a brush set to '0' hardness and opacity and flow set to 50% and painted over the hotspot. I then dialled the opacity of the layer down to about 80% and applied a small amount of noise with monochrome unticked (not selected). I did the same as above for the hand and her upper lip.
If this photo is destined for print then I suggest using the clone/healing brush tool instead of a sampled color so as to better match the texture of her skin. It's a bit of a longer process and you have to excercise more care but the end result is usually better. Just be carefull at the edges where the hotspot meets the unblown out areas of skin.
If anything I did is not clear, let me know and I'll help you out.
Hope this helps.