Stan,
Referring specifically to the fact that you're shooting a D100 (like I am), I've found (and learned from other folks shooting the same camera) that you can achieve very sharp results from the D100, if you apply a little bit of tradecraft:
(a) if at all possible, put it on a tripod - should be self-explanatory
(b) find (by experimentation) the 'sweet spot' of each of your lenses - and they are NOT usually at the same aperture. My Nikon 80-200/2.8 gives me the sharpest image at about f5.6 while the Nikkor 35-70/2.8 is sharpest at about f8 and my Sigma 18-35 is sharpest at a spot half-way between. Granted, the differences aren't a whole bunch... each of these three lenses is pretty sharp.
(c) set your in-camera sharpening to OFF. The sharpening routines in the D100 are noticeably lacking (go back and read the first couple months of reviews of the D100 and you'll find that it was probably the most complained-about 'feature' of the D100 by early adopters).
Instead, use either Nikon's CAPTURE or one of the third-party RAW products to sharpen the images. I use CAPTURE and can batch process a whole day's shoot in just a few minutes, if all I'm doing is sharpening. Of course, normally I also adjust white balance and may be doing a bit of exposure correction at the same time.
Most of the time, I tend to soften the image a bit, especially when I'm photographing a woman with less than perfect skin (and I've yet to find one of those out there)... not too many ladies want all the pores and blemishes jumping out at them.
Hope this helps with some specifics for the D100.
